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Reza Ebrahimifard PDF Print E-mail

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Current position

Research associate and PhD student, Institute for Microsensors, -Actuators and –Systems (IMSAS), University of Bremen


 

Background

BSc. of Material Science and Engineering, University of Tehran, Iran

MSc. of Material Science and Engineering, University of Tehran, Iran

 

Project description

Investigation and detection of melanoma cancer cells in lymph fluid using microfluidics technology. In this research project both infrared (IR) analysis and photoacoustic (PA) measurement were selected for the detection and analysis of cells.

In the IR method, cells will be exposed by mid-IR electromagnetic wave in the region of 3-4 µm. Mammalian cells compose of phospholipid molecules and these molecules consist of alkane chain (polymers of CH2). The stretch vibrations of CH2 place in 3-4 µm and accordingly, mid-IR exposure interacts with cells in this region. This interaction can differentiate healthy and malignant cells due to the differences in their membrane properties.

Photoacoustics is a phenomenon based on optical absorption. In PA a pulsed source excites sample in an appropriate frequency. When a cell receives a pulse, it absorbs the light and then there will be a conversion of optical to thermal to mechanical energy in the form of expansion and contraction. So, regular cell movement because of consecutive pulse collision results in propagation of acoustic waves in surrounding media.

 

Supervisors

Prof. Dr. Michael Vellekoop

 

Courses

Courses presented in network meeting in Delft Sept. 2013

Courses presented in network meeting in Copenhagen Aug. 2014

''Introduction to microtechnology'', University of Bremen, 2013

 

Network Meetings

Delft, Netherlands, September, 2013

Copenhagen, Denmark, August 2014

Bremen, Germany, Feburary 2015

 

Publications and Conferences

Reza Ebrahimifard, Sander van den Driesche, Michael J. Vellekoop, D2O-based microfluidics for in vitro IR cell analysis, Transducers 2015, Anchorage, USA, June 2015

 

Membership

Institute for Microsensors, -Actuators and –Systems (IMSAS)

Microsystems Center Bremen (MCB)